Publications by authors named "Andrea Faour"

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by persistent inflammation, joint pain, and progressive cartilage and bone erosion. Despite advancements in RA management with disease-modifying antirheumatic drugs (DMARDs) and biologics, some patients remain refractory to conventional treatments. Tetracyclines, such as minocycline and doxycycline, exhibit anti-inflammatory and immunomodulatory properties, making them potential supplementary treatments.

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Article Synopsis
  • Spinal muscular atrophy (SMA) is a rare inherited disease that varies in symptoms and requires diverse care for affected patients, prompting a systematic literature review of pharmacoeconomic evaluations for existing therapies.
  • The review focused on studies published in English after 2016, analyzing 14 relevant studies for quality and reporting standards using established checklists, and highlighting the need for cost-effectiveness analysis even for high-cost treatments.
  • The findings stress the importance of establishing specific willingness to pay thresholds for orphan medicines to ensure that SMA patients have access to safe and effective therapies, while also emphasizing the necessity of considering new information in medication decisions.
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