Photodynamic endometrial ablation for the treatment of dysfunctional uterine bleeding: a preliminary report.

Background And Objectives: To evaluate feasibility and functional effects of photodynamic endometrial ablation (PEA) in patients.

Study Design/patients And Methods: A total of 15 PEAs has been performed in 11 patients using topically applied 5-aminolevulinic acid (ALA) solutions and a balloon-light diffuser (160 J/cm(2), 635 nm). Uterine bleeding intensity has been determined on a daily basis 3 months prior to and up to 6 months after endometrial ablation using an analogous scale scoring from 1 (spotting) to 6 U (severe bleeding).