Publications by authors named "Andrea Exposito-Marrero"
Is the long-term mortality similar in COVID-19 and community-acquired pneumonia?
Front Med (Lausanne)
October 2023
Article Synopsis
- The study investigates the long-term mortality rates associated with COVID-19 and community-acquired pneumonia (CAP) in patients who were hospitalized and later discharged.
- It utilizes a retrospective analysis of two cohorts, applying Bayesian logistic regression to control for confounding factors while assessing mortality outcomes after one year.
- Findings suggest that both types of pneumonia have comparable long-term mortality rates, with no significant difference after adjustments, indicating a low probability of distinguishing between them based on mortality risk.
Introduction: Elexacaftor/tezacaftor/ivacaftor (ETI) was used through the early access programme in Spain from December 2019 in cystic fibrosis (CF) patients with homozygous or heterozygous F508del mutation with advanced lung disease.
Methodology: Multicentre, ambispective, observational, study in which 114 patients in follow-up in 16 national CF units were recruited. Clinical data, functional tests, nutritional parameters, quality of life questionnaires, microbiological isolates, number of exacerbations, antibiotic treatments and side effects were collected.
Purpose: Acute exacerbations of COPD (AECOPD) are important factors contributing to mortality risk. The rate of exacerbations varies overtime. An inconsistent pattern of exacerbation occurrence is a common finding.
View Article and Find Full Text PDFBackground: Chronic obstructive pulmonary disease (COPD) is a complex and heterogeneous condition, in which taking into consideration clinical phenotypes and multimorbidity is relevant to disease management. Network analysis, a procedure designed to study complex systems, allows to represent connections between the distinct features found in COPD.
Methods: Network analysis was applied to a cohort of patients with COPD in order to explore the degree of connectivity between different diseases, taking into account the presence of two phenotypic traits commonly used to categorize patients in clinical practice: chronic bronchitis (CB /CB ) and the history of previous severe exacerbations (Ex /Ex ).