Publications by authors named "Andrea E Jaimes"

Purpose: To introduce alternating current-controlled, conductive ink-printed marker that could be implemented with both custom and commercial interventional devices for device tracking under MRI using gradient echo, balanced SSFP, and turbo spin-echo sequences.

Methods: Tracking markers were designed as solenoid coils and printed on heat shrink tubes using conductive ink. These markers were then placed on three MR-compatible test samples that are typically challenging to visualize during MRI scans.

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Background: Intramyocardial guidewire navigation is a novel technique that allows free transcatheter movement within ventricular muscle. Guidewire radial depth, between endocardial and epicardial surfaces, is ambiguous by x-ray and echocardiography.

Objectives: The aim of this study was to develop a simple tool, EDEN (Electrocardiographic Radial Depth Navigation), to indicate radial depth during intramyocardial guidewire navigation.

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MIRTH (Myocardial Intramural Remodeling by Transvenous Tether) is a transcatheter ventricular remodeling procedure. A transvenous tension element is placed within the walls of the beating left ventricle and shortened to narrow chamber dimensions. MIRTH uses 2 new techniques: controlled intramyocardial guidewire navigation and EDEN (Electrocardiographic Radial Depth Navigation).

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Article Synopsis
  • Researchers developed a new method to effectively measure left ventricular contractility and compliance using pressure-volume loops during dynamic preload reduction, combining cardiovascular magnetic resonance (CMR) imaging and invasive pressure measurements.
  • In a study with 16 swine, various models (including ones with aortic banding and ischemic cardiomyopathy) were used to evaluate changes in contractility and compliance through dynamic occlusion of the inferior vena cava.
  • Results showed that animals with ischemic cardiomyopathy had significantly lower contractility and increased compliance compared to naïve swine, while measurements from CMR and traditional catheter techniques demonstrated good agreement.
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Background: Left ventricular outflow tract obstruction complicates hypertrophic cardiomyopathy and transcatheter mitral valve replacement. Septal reduction therapies including surgical myectomy and alcohol septal ablation are limited by surgical morbidity or coronary anatomy and high pacemaker rates, respectively. We developed a novel transcatheter procedure, mimicking surgical myotomy, called Septal Scoring Along the Midline Endocardium (SESAME).

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