Publications by authors named "Andrea E Geddes"
Article Synopsis
- * The study found higher proportions of CD4+ T cells in women’s tumor and lymph node samples, while CD8+ T cells were more prevalent in their uninvolved colon compared to men.
- * Differential gene expression related to immune functions was observed in women, suggesting that these immune system disparities may explain the survival advantages seen in female CRC patients.
Background: The focused abdominal sonography for trauma (FAST) examination has been reported to be unreliable in pelvic fracture patients. Additionally, given the advent of new therapeutic interventions, such as resuscitative endovascular balloon occlusion of the aorta (REBOA), rapid identification of intra-abdominal hemorrhage compared with Zone III hemorrhage may guide different therapeutic strategies. We hypothesized that FAST is reliable for detecting clinically significant intra-abdominal hemorrhage in the face of complex pelvic fractures.
View Article and Find Full Text PDFBackground: A 2015 American Association for the Surgery of Trauma trial reported a 32% mortality for pelvic fracture patients in shock. Angioembolization (AE) is the most common intervention; the Maryland group revealed time to AE averaged 5 hours. The goal of this study was to evaluate the time to intervention and outcomes of an alternative approach for pelvic hemorrhage.
View Article and Find Full Text PDFBackground: We implemented expanded screening criteria for blunt cerebrovascular injuries (BCVIs) in an attempt to capture the remaining 20% of patients not historically identified with earlier protocols. We hypothesized that these expanded criteria would capture the additional 20% of BCVI patients not previously identified.
Methods: Screening criteria for BCVI were expanded in 2011 after identifying new injury patterns.