Publications by authors named "Andrea De Salvo"

Article Synopsis
  • Germ cell tumors (GCT) are a type of brain cancer that mostly affects teenagers and young adults, but they can often be treated successfully with chemotherapy and radiation therapy.
  • A study looked at 17 patients treated for these tumors, and most of them had good results, with only one person having a relapse.
  • Proton beam radiation (PBT) was shown to be a safe and effective treatment, helping to keep patients' brains working well without causing serious side effects.
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BACKGROUNDSevere forms of idiopathic nephrotic syndrome (INS) require prolonged immunosuppressive therapies and repeated courses of high-dose glucocorticoids. Mesenchymal stromal cells (MSCs) have promising immunomodulatory properties that may be employed therapeutically to reduce patient exposure to medications and their side effects.METHODSWe performed a phase I open-label trial assessing safety and feasibility of autologous bone marrow-derived MSCs (BM-MSCs) in children and young adults with severe forms of steroid-dependent nephrotic syndrome.

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Background: Cancer is very disruptive in adolescence and hospitalizations interfere with this development stage in becoming independent, developing social relationships, and making plans for the future. A major challenge in the care of adolescents with cancer is being able to enhance their quality of life. The aim of this project is to increase our understanding of how adventure therapy influenced quality of life for adolescents with cancer.

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