Publications by authors named "Andrea Dan Ryals"

Background And Objective: The recent introduction of antivirals for the treatment of the hepatitis C virus opens new frontiers but also poses a significant burden on public health systems. This paper presents a simulation study in which model predictive control (MPC) is proposed for optimizing the therapy aiming to obtain a reduction of the costs of therapy, while maintaining the best pharmacological control of the infection.

Methods: A dynamic model describing the evolution of hepatitis C is deployed as internal model for MPC implementation, using nominal values of parameters.

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