Publications by authors named "Andrea D Freitas"
A Cluster of Diutina catenulata Funguria in Patients with Coronavirus Disease 2019 (COVID-19) Hospitalized in a Tertiary Reference Hospital from Rio de Janeiro, Brazil.
Curr Microbiol
September 2024
Article Synopsis
- During the COVID-19 pandemic, fungal infections like pulmonary aspergillosis and invasive candidiasis gained attention, with a specific focus on a rare pathogen, Diutina catenulata, isolated from patients' urine.
- A study identified nine strains from six patients needing ventilator support and urinary catheters, all of whom were unvaccinated against COVID-19, and revealed consistent morphological and biochemical profiles among the isolates.
- Whole-genome sequencing showed minimal genetic variation among the strains, suggesting they were part of a cluster of D. catenulata infections associated with COVID-19.
Meningeal sporotrichosis is rare and occurs predominantly in immunosuppressed individuals. This retrospective study explored clinical and laboratory characteristics, treatment, and prognosis of patients with disseminated sporotrichosis who underwent lumbar puncture (LP) at a Brazilian reference center from 1999 to 2020. Kaplan-Meier and Cox regression models were used to estimate overall survival and hazard ratios.
View Article and Find Full Text PDFParacoccidioidomycosis in people living with HIV/AIDS: A historical retrospective cohort study in a national reference center for infectious diseases, Rio de Janeiro, Brazil.
PLoS Negl Trop Dis
June 2022
Paracoccidioidomycosis (PCM) is one of the main endemic systemic mycoses in Latin America, usually occurring in rural areas. When PCM occurs simultaneously with underlying immunosuppressive conditions, it can present as an opportunistic disease. Between 2000 and 2017, literature reported around 200 PCM cases in people living with HIV/AIDS (PLWHA).
View Article and Find Full Text PDFArticle Synopsis
- The text discusses two cases of acute pulmonary histoplasmosis observed in Rio de Janeiro, where both patients had a recent history of COVID-19 but no common exposure to the fungus.
- Despite negative standard tests, advanced methods like Western Blot and PCR confirmed the diagnosis, leading to timely treatment with itraconazole.
- The cases imply a potential link between COVID-19 recovery and increased risk of developing acute histoplasmosis, highlighting the need for awareness among clinicians in endemic regions.
Neuroparacoccidioidomycosis (NPCM) is a rare and severe clinical presentation of paracoccidioidomycosis (PCM). We performed a retrospective cohort study at the Evandro Chagas National Institute of Infectious Diseases (INI/Fiocruz), a reference center for PCM in the state of Rio de Janeiro, Brazil. All cases of PCM admitted to the INI/Fiocruz from January 2007 to December 2019 were reviewed.
View Article and Find Full Text PDFHepatic Disease with Portal Hypertension and Acute Juvenile Paracoccidioidomycosis: A Report of Two Cases and Literature Review.
Mycopathologia
October 2017
Paracoccidioidomycosis (PCM) is a neglected systemic mycosis endemic to Latin America caused by dimorphic fungi of the genus Paracoccidioides. The acute juvenile PCM is a severe type of presentation that usually affects young vulnerable patients and rarely progresses to portal hypertension. Here, two cases of liver disease and portal hypertension as complications of acute juvenile PCM are reported.
View Article and Find Full Text PDFAcute Paracoccidioidomycosis Due to Paracoccidioides brasiliensis S1 Mimicking Hypereosinophilic Syndrome with Massive Splenomegaly: Diagnostic Challenge.
PLoS Negl Trop Dis
April 2016
Corynebacterium striatum is a potentially pathogenic microorganism with the ability to produce outbreaks of nosocomial infections. Here, we document a nosocomial outbreak caused by multidrug-resistant (MDR) C. striatum in Rio de Janeiro, Brazil.
View Article and Find Full Text PDFMycobacterium massiliense BRA100 strain recovered from postsurgical infections: resistance to high concentrations of glutaraldehyde and alternative solutions for high level disinfection.
Acta Cir Bras
October 2010
Purpose: To evaluate the minimum inhibitory concentration (MIC) of GTA against these microorganisms and alternative disinfectants for high-level disinfection (HLD).
Methods: Reference mycobacteria and clinical M. massiliense strains were included in this study.