Publications by authors named "Andrea D Belalcazar"
The transsulfuration pathway, through which homocysteine from the methionine cycle provides sulfur for cystathionine formation, which may subsequently be used for glutathione synthesis, has not heretofore been identified as active in mammary cells. Primary human mammary epithelial cells (HMEC's) were labeled with S-methionine for 24 hours following pretreatment with a vehicle control, the cysteine biosynthesis inhibitor propargylglycine or the gamma-glutamylcysteine synthesis inhibitor buthionine sulfoximine. Cell lysates were prepared and reacted with glutathione-S-transferase and the fluorescent labeling compound monochlorobimane to form a fluorescent glutathione-bimane conjugate.
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- The Drosophila wing has a complex structure with a transparent membrane supported by veins, featuring ridges that contribute to its unique shape.
- Research shows that the dorsal (top) wing epithelium defines the wing's membrane topography, as seen through changes in wing hair placement and membrane structure.
- Studies of honeybees and parasitic wasps reveal similar dorsal control over wing topography, indicating that this characteristic may be a fundamental trait in primitive insects.