Publications by authors named "Andrea D'Argenio"

Article Synopsis
  • Clonal evolution in chronic lymphocytic leukemia (CLL) happens in both treated and untreated patients, impacting disease outcomes.
  • The study found that while all CLL patients experience clonal evolution, it progresses more rapidly in cases of disease worsening.
  • Specific changes in the frequency of nucleotide variants in key CLL genes may serve as markers for identifying patients with a higher risk of poor outcomes.
View Article and Find Full Text PDF

The given and family names of two co-authors were incorrect in the published article. The correct spelling should read as: Sampath Chandra Prasad and Vinagolu K Rajasekhar.

View Article and Find Full Text PDF

Tumours can be viewed as aberrant tissues or organs sustained by tumorigenic stem-like cells that engage into dysregulated histo/organogenetic processes. Paragangliomas, prototypical organoid tumours constituted by dysmorphic variants of the vascular and neural tissues found in normal paraganglia, provide a model to test this hypothesis. To understand the origin of paragangliomas, we built a biobank comprising 77 cases, 18 primary cultures, 4 derived cell lines, 80 patient-derived xenografts and 11 cell-derived xenografts.

View Article and Find Full Text PDF