Publications by authors named "Andrea Carolina Pinheiro de Freitas"

Melasma is acquired hyperpigmentation that mainly affects the face, can cause negative changes in self-esteem, and mostly affects women. Treatment is difficult, and different drugs can be used in mono or combination therapy. In this article, we present a brief overview of melasma, how to evaluate it, and a synthesis of the most commonly used topical therapies and their indications, including sunscreens, pharmacological agents, and plant extracts.

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Background: The initial contact of consumers when choosing sunscreens is through the trademark, packaging, perfume, and tactile feeling of the product, outlining the popular practice of sensory science.

Aims: To describe the sensory and physical-mechanical profile of commercial sunscreens through sensory and instrumental analyses related to principal component analysis (PCA).

Methods: Seven commercial sunscreens available on the Brazilian market and with a solar protection factor (SPF) of 30 were evaluated.

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Article Synopsis
  • The study developed a new drug delivery system using organogels (ORGs) that combined oleic acid-lanolin, poloxamer, and lidocaine to evaluate their properties and effectiveness.
  • The results showed that varying the concentrations of lanolin and poloxamer changed the physical properties of the organogels and influenced the release rates of lidocaine.
  • The ORG system demonstrated low cytotoxicity and provided longer-lasting local anesthesia effects, suggesting it could be a better alternative for delivering topical anesthetics compared to current options.
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