Insight on cytotoxic NHC gold(I) halide complexes evaluated in multifaceted culture systems.

Gold complexes can be a useful system in the fight against cancer. Although many studies have been carried out on in vitro 2D cell culture models embryotoxic assays are particularly lacking. Embryotoxicity and DNA damage are critical concerns in drug development.

Individually Cultured Bovine Zygotes Successfully Develop to the Blastocyst Stage in an Extremely Confined Environment.

The possibility of detecting the developmental competence of individually cultured embryos through analysis of spent media is a major current trend in an ART setting. However, individual embryo culture is detrimental compared with high-density group culture due to the reduced concentration of putative embryotropins. The main aim of this study was to identify an individual culture system that is not detrimental over high-density group culture in the bovine model.

Lightweighting in the automotive industry as a measure for energy efficiency: Review of the main materials and methods.

The increasing emissions of greenhouse gases (GHG) and pollutants like particulate matter and nitrogen oxides (NOx) have led to environmental concerns. Hybrid and electric powertrains are being introduced as means to reduce pollutant emissions, especially at the local level. Additionally, the finite availability of fossil fuel sources, which are used to produce gasoline and diesel, highlights the need for alternative technical solutions.

Enhanced solute transport and steady mechanical stimulation in a novel dynamic perifusion bioreactor increase the efficiency of the culture of ovarian cortical tissue strips.

We report the development and preliminary evaluation of a novel dynamic bioreactor to culture ovarian cortical tissue strips that leverages tissue response to enhanced oxygen transport and adequate mechanical stimulation. multistep ovarian tissue static culture followed by mature oocyte generation, fertilization, and embryo transfer promises to use the reserve of dormant follicles. Unfortunately, static culture of ovarian tissue does not promote development of primordial to secondary follicles or sustain follicle viability and thereby limits the number of obtainable mature oocytes.

The Radium Terrors. Science Fiction and Radioactivity before the Bomb.

At the beginning of the 20th century the collective imagination was fascinated and terrified by the discovery of radium. A scientific imagery sprang up around radioactivity and was disseminated by public lectures and newspaper articles discussing the ambiguous power of this strange substance. It was claimed that radium could be used to treat cholera, typhus and tuberculosis, but at the same time there were warnings that it could be used for military purposes.

Italian news coverage of radiation in the early decades of the twentieth century: A qualitative and quantitative analysis.

This work uses a qualitative approach coupled with a quantitative software-based methodology to examine the Italian news media coverage of radiation in the early decades of the twentieth century. We analyze 80 news stories from two of the most influential Italian newspapers from that time: La Stampa (a daily newspaper) and La Domenica del Corriere (an Italian Sunday supplement). While much of previous research on media coverage of scientific topics was generally focused on present-day news, our work revolves around the ground-breaking discovery of X-rays and radioactivity at the dawn of the last century.