Introduction: The predictability of any epidemic is highly uncertain, especially regarding a new emerging pathogen such as SARS-CoV-2.
Objectives: We studied the predictability of the incidence series of COVID-19 in Chile (whole country) and three regions with different population sizes. The analysis included the period intervened by vaccination campaigns and when new variants of the SARS-CoV-2 virus arrived.
Background: The relative importance of congenital malformations as a cause of death in the first year of life is increasing along with the control of preventable causes of perinatal mortality.
Aim: To identify risk factors for congenital malformations.
Patients And Methods: Retrospective case-control study of births registered in the database of The Latin American Collaborative Study of Congenital Malformations (ECLAMC), in the period 2001-2010.