Dynamics of Intraprocedural Dominant Frequency Identifies Ablation Outcome in Persistent Atrial Fibrillation.

The role of dominant frequency (DF) in tracking the efficiency of a stepwise catheter ablation (step-CA) in persistent atrial fibrillation (peAF) remains poorly studied. We hypothesized that the DF time-course during step-CA displays divergent patterns between patients in whom a step-CA successfully restores long-term sinus rhythm (SR) and those with recurrence. This study involved 40 consecutive patients who underwent a step-CA for peAF (sustained duration 19 ± 11 months).

Severe and uniform bi-atrial remodeling measured by dominant frequency analysis in persistent atrial fibrillation unresponsive to ablation.

Background: High values of ECG and intracardiac dominant frequency (DF) are indicative of significant atrial remodeling in persistent atrial fibrillation (peAF). We hypothesized that patients with peAF unresponsive to ablation display higher ECG and intracardiac DFs than those remaining in sinus rhythm (SR) on the long term.

Methods: Forty consecutive patients underwent stepwise ablation for peAF (sustained duration 19 ± 11 months).

Recipient Atrial Fibrillation Manifesting as an Irregular Monomorphic Atrial Tachycardia in the Donor Heart.

A 63-year-old man presented with a 1-year history of atrial tachycardia (AT) 6 years after orthotopic heart transplantation with bicaval anastomosis. Twelve-lead electrocardiogram showed monomorphic AT with isoelectric intervals across all leads and strikingly irregular PP intervals. At electrophysiology study, the native left atrium's rhythm was atrial fibrillation (AF) while the donor atria exhibited centrifugal activation of irregular cycle length originating from a site along the left atrial anastomosis.

A High Baseline Electrographic Organization Level Is Predictive of Successful Termination of Persistent Atrial Fibrillation by Catheter Ablation.

Objectives: This study sought to investigate whether the level of organization of electrocardiographic (ECG) signals based on novel indexes is predictive of persistent atrial fibrillation (pAF) termination by catheter ablation (CA).

Background: Whether the level of ECG organization in pAF is correlated with the restoration of sinus rhythm by CA remains unknown.

Methods: Thirty consecutive patients who underwent stepwise CA for pAF (sustained duration 19 ± 11 months) were included in the study (derivation cohort).

Nonlinear analysis of right atrial electrograms predicts termination of persistent atrial fibrillation within the left atrium by catheter ablation.

The termination of long-standing persistent atrial fibrillation (LS-pAF) can be achieved by stepwise catheter ablation (step-CA) within the left atrium (LA). Our study aims to applying complexity measures derived from nonlinear time series analysis in order to characterize LS-pAF in terms of organization and to identify patients in whom AF can be terminated from those in whom AF cannot be terminated by step-CA within the LA. A total of 33 consecutive patients (age 61  ±  7 years, sustained AF duration 19  ±  11 months) with LS-pAF underwent step-CA.