Publications by authors named "Andrea Borin"

Article Synopsis
  • The study investigates how gender affects heart remodeling and the risk of heart failure (HF) after acute coronary syndrome (ACS), using data from the CORALYS registry.
  • Among 14,699 patients, 31% were women, who had different health profiles compared to men, showing higher rates of hypertension and diabetes but lower rates of smoking and previous heart attacks.
  • Results indicated that women had a higher incidence of both HF hospitalizations and cardiovascular death, establishing female sex as an independent risk factor for these outcomes after ACS.
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Article Synopsis
  • The study investigates the risk factors for hospitalization due to heart failure (HF) in patients with acute coronary syndrome (ACS) who have not previously experienced HF or left ventricular dysfunction.
  • It analyzed data from 14,699 patients across 16 European centers using both Cox regression and machine learning models, identifying key risk factors such as reduced renal function and left ventricular ejection fraction.
  • The CORALYS HF score successfully pinpointed high-risk patients using commonly available information at discharge, indicating a need for further strategies to prevent HF in this specific group.
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Background The impact of complete revascularization (CR) on the development of heart failure (HF) in patients with acute coronary syndrome and multivessel coronary artery disease undergoing percutaneous coronary intervention remains to be elucidated. Methods and Results Consecutive patients with acute coronary syndrome with multivessel coronary artery disease from the CORALYS (Incidence and Predictors of Heart Failure After Acute Coronary Syndrome) registry were included. Incidence of first hospitalization for HF or cardiovascular death was the primary end point.

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Despite the growing experience with MitraClip in the broad spectrum of mitral regurgitation (MR), limited data are available regarding the independent prognostic role on survival of different mitral regurgitation etiology subtypes. We sought to evaluate the impact of flail leaflet etiology in a large series of patients with primary MR (PMR) who underwent MitraClip treatment. The study included 588 patients with significant PMR from the multicenter GIOTTO (Italian Society of Interventional Cardiology [GIse] registry Of Transcatheter treatment of mitral valve regurgitaTiOn), stratified into 2 groups according to MR etiology: flail (n = 300) and flail (n = 288).

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Background: Previous studies investigating predictors of Heart Failure (HF) after acute coronary syndrome (ACS) were mostly conducted during fibrinolytic era or restricted to baseline characteristics and diagnoses prior to admission. We assessed the incidence and predictors of HF hospitalizations among patients treated with percutaneous coronary intervention (PCI) for ACS.

Methods And Results: CORALYS is a multicenter, retrospective, observational registry including consecutive patients treated with PCI for ACS.

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Background: Data regarding management of patients with unprotected left main coronary artery in-stent restenosis (LM-ISR) are scarce.

Objectives: This study investigated the safety and effectiveness of percutaneous coronary intervention (PCI) vs. coronary artery bypass grafting (CABG) for the treatment of unprotected LM-ISR.

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Introduction: The impact of Covid-19 on the survival of patients presenting with acute coronary syndrome (ACS) remains to be defined.

Methods: Consecutive patients presenting with ACS at 18 Centers in Northern-Italy during the Covid-19 outbreak were included. In-hospital all-cause death was the primary outcome.

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Background: Investigations demonstrated a decrease of admissions for myocardial infarction (MI) during the CoronaVirus Disease-19 (COVID-19) outbreak. No study has evaluated the time required to reverse this downward curve of MI admissions.

Methods: This is a retrospective analysis on patients (N = 2415) admitted to the Emergency Departments for acute MI in nine Italian centers.

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