Purpose: We assessed the influence of renal ischemia on long-term global renal function after laparoscopic partial nephrectomy in patients with 2 functioning kidneys in a large, multicenter cohort.
Materials And Methods: Collected data included demographic, clinical and surgical characteristics, tumor parameters and renal function outcomes at 4 institutions in a total of 401 patients with 2 functioning kidneys who underwent laparoscopic partial nephrectomy. Renal function was assessed in the immediate postoperative period (days 1 to 3) and at last followup (greater than 1 month) using the estimated glomerular filtration rate calculated by the 4-variable Modification of Diet in Renal Disease equation.
Objectives: To retrospectively evaluate clinical, tumor, and surgical factors that were potential predictors of postoperative unilateral renal function after laparoscopic and open partial nephrectomy.
Methods: Sixty-five patients who had undergone partial nephrectomy and had postoperative renal scintigraphy performed were evaluated on the basis of multiple factors as potential predictors of postoperative renal function in the ipsilateral kidney. These factors include patient age, indication for nephron-sparing surgery, type of procedure (laparoscopic vs open), preoperative and postoperative glomerular filtration rate, tumor depth, radiographic and pathologic tumor size, warm ischemia time, and intraoperative visual assessment of functional renal parenchyma preserved.