Stromal α-Smooth Muscle Actin Positivity Is Associated With High-Risk Basal Cell Carcinomas.

The presence of myofibroblast differentiation has been proposed as an invading mechanism in basal cell carcinomas. However, small studies regarding α-smooth muscle actin positivity have led to conflicting results. This review of 100 cases examines the association between α-smooth muscle actin positivity on immunohistochemical studies and the clinical and histopathological characteristics of the tumor, including tumor size, thickness, subtype, topography, ulceration, 5-year recurrence rate, and age at diagnosis.

Dermoscopic Aspects of Cutaneous Adverse Drug Reactions.

Background: Little is known about the dermoscopic evaluation of cutaneous adverse drug reactions (CADRs).

Objectives: To evaluate the dermoscopic patterns of CADRs and identify those associated with severe cutaneous adverse reactions to drugs (SCARDs).

Patients And Methods: Patients included in this study from May 2015 to April 2016 had presented with CADRs.

Tumor in the plantar region: dermatofibrosarcoma protuberans in an infrequent topography.

Dermatofibrosarcoma protuberans is a rare mesenchymal tumor; it is locally aggressive and presents high rates of local recurrence. It may present as a nodular or plaque vegetating lesion. It mainly affects the trunk and proximal limbs, being rare in the distal extremities.