Development and application of a novel multi-channel in vitro electrical stimulator for cellular research.

Background: Exposure to electric fields affects cell membranes impacting their potential and altering cellular excitability, nerve transmission, or muscle contraction. Furthermore, electric stimulation influences cell communication, migration, proliferation, and differentiation, with potential therapeutic applications. In vitro platforms for electrical stimulation are valuable tools for studying these effects and advancing medical research.

Baclofen modulates the immune response after spinal cord injury with locomotor benefits.

Background And Purpose: Spinal cord injury (SCI) is a neurological condition that affects motor and sensory functions below the injury site. The consequences of SCI are devastating for the patients, and although significant efforts have been done in the last years, there is no effective therapy. Baclofen has emerged in the last few years as an interesting drug in the SCI field.