Influence of leukotriene inhibitor montelukast on wound contraction and cutaneous healing process in rats.

Background: Wound contractures can cause severe deformities and disabilities. Recent studies have suggested that leukotriene receptor antagonists have an inhibitory effect on the healing contraction process. This study aimed to evaluate the influence of the leukotriene inhibitor montelukast on the cutaneous healing process and the wound contraction phenomenon in rats.

[Surgical bladder wounds treated with Orbignya phalerata aqueous extract: controlled study in rats].

Introduction: Wound healing is a complex process that deals with different biological and immunological systems and is essential to keep the organism integrity. Three well-defined phases occur: inflammatory, proliferative and maturation. A failure or lengthy phase may result in a delay or absence of it.