Publications by authors named "Andre P Dos Santos"

Article Synopsis
  • - This study investigates the link between alcohol consumption and falls among people with HIV (PWH), highlighting that falls are a major health issue, especially for older adults and PWH.
  • - Researchers categorized participants (315 PWH, mostly male, average age 52) into drinking levels (none, non-hazardous, hazardous) and analyzed the relationship between their drinking habits and fall incidents using various statistical methods.
  • - Findings revealed that hazardous drinkers had a significantly higher risk of falls and recurrent falls compared to non-hazardous drinkers, but the amount of alcohol consumed daily in grams did not show a clear connection to fall risk.
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Article Synopsis
  • The study aimed to explore how low handgrip strength (HGS) relates to the risk of falls in middle-aged and older adults, analyzing data from the Brazilian Longitudinal Study of Aging.
  • It involved 8,112 participants aged 50 to 105, revealing that 21.5% experienced at least one fall and that HGS declines steadily with age.
  • The findings indicate that low HGS significantly contributes to fall risk in individuals through their 50s and continues to be an important factor until the 80s, even when accounting for other health variables.
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  • This study focused on creating predictive models for fat mass ratio (FMR) in individuals living with HIV, using various body measurement techniques to assess body composition.
  • A total of 106 Brazilian participants were evaluated, and six models were developed with varying effectiveness in predicting FMR based on different health-related and anthropometric factors.
  • The most effective model combined several measurements and showed strong agreement with traditional methods, improving the understanding of body composition and potential lipodystrophy diagnosis in people with HIV.
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Background: It is plausible that depression symptoms and disrupting sleep quality were differently affected according to the rigidity of social distancing during the COVID-19 outbreak.

Objective: To describe and compare depression symptoms and sleep quality amongst older Brazilian and Chinese women who were submitted to different social distancing measures (less rigid (Brazil) versus more rigid (China)).

Methods: This observational cross-sectional study assessed urban older women who underwent home confinement with less (Brazil; n=1015) or more (China; n=644) rigidity.

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Background: The implementation of social distancing measures during covid-19 influenced health outcomes and population´s behaviors, and its rigidity was very different across countries. We aimed to verify the association between the rigidity of social distancing measures of covid-19 first wave with depression symptoms, quality of life and sleep quality in older adults.

Methods: This is a cross-sectional study including 1023 older adults (90% women; 67.

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Background: Sarcopenic obesity (SO) is a clinical and functional disease characterized by the coexistence of obesity and sarcopenia. Resistance training (RT) characteristics for older adults with sarcopenia or obesity are already well established in the scientific literature. Nonetheless, we still do not know how detailed the RT protocols are described for older adults with SO.

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Introduction: The time spent in different physical activity (PA) intensities is associated with sarcopenia risk for community-dwelling older women.

Aim: To evaluate the role of sitting time and physical activity (PA) level as predictors of sarcopenia odds.

Methods: In a cross-sectional study, physically independent older women (n = 67) performed the six-minute walk test to identify functional limitation (≤ 400 m).

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People living with HIV (PWH) experience an accelerated aging process. There is no anthropometric predictive model for appendicular skeletal muscle mass (ASM) in PWH. This study develops anthropometric models to predict and validate ASM measured by dual energy x-ray absorptiometry (DXA) in PWH; DXA scans were obtained for 125 PWH (male = 74; age >18 years) on antiretroviral therapy.

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Background: Appendicular skeletal muscle mass (ASM) obtained from dual-energy x-ray absorptiometry (DXA) is recommended to quantify sarcopenia, but has limited availability in disadvantaged-income countries, moreover in an epidemiological context. Predictive equations are easier and less costly to apply, but a review of all available models is still lacking in the scientific literature. The objective of this work is to map, with a scoping review, the different proposed anthropometric equations to predict ASM measured by DXA.

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The regular practice of physical activity helps in the prevention and control of several non-communicable diseases. However, evidence on the role of physical activity in mitigating worsening clinical outcomes in people with COVID-19 is still unclear. The aim of this study was to verify whether different levels of physical activity provide protection for clinical outcomes caused by SARS-CoV-2 infection.

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Objective: This review aimed to compile the evidence on PA and clinical outcomes of people receiving a positive diagnosis of covid-19.

Design: Systematic review.

Methods: The search was performed in five databases: EMBASE, MEDLINE via PubMed portal, Scopus, SPORTDiscus via EBSCO platform, and Web of Science.

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People living with HIV (PWH) experience an accelerated reduction in bone mineral content (BMC), and a high risk of osteopenia and osteoporosis. Anthropometry is an accurate and low-cost method that can be used to monitor changes in body composition in PWH. To date, no studies have used anthropometry to estimate BMC in PWH.

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Resistance training with blood flow restriction (RTBFR) allows physically impaired people living with HIV (PWH) to exercise at lower intensities than traditional resistance training (TRT). But the acute and chronic cardiac and metabolic responses of PWH following an RTBFR protocol are unknown. The objective was to compare the safety of acute and chronic effects on hemodynamic and lipid profiles between TRT or RTBFR in PWH.

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Article Synopsis
  • The study investigates the use of bioelectrical impedance vector analysis (BIVA) to assess body composition, hydration, and physical performance in older adults, particularly focusing on those with sarcopenia (muscle loss condition).
  • It involved 94 older adults (ages 60-85) and found that both classic and specific BIVA effectively identified sarcopenia in women, but had limitations with men; classic BIVA was more reliable in distinguishing muscle index and performance.
  • The findings suggest that classic BIVA is a valuable tool for monitoring risks related to sarcopenia in older adults, especially for female subjects, while specific BIVA showed less distinction.
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Objectives: Absolute handgrip strength and adjusted by body mass index are useful to identify age-related conditions. However, these values are not accurate for older adults with extreme body size because of the nonlinear relationship between strength, height, and body mass. The purpose of this study was to determine cut-off points for age-related conditions of older adults using allometric coefficients to normalize grip strength by body size.

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Background: To propose cut-off points for older adults' weakness for upper and lower limbs muscle strength normalized by body size with the ratio standard/muscle quality and allometric scaling.

Methods: Ninety-four community-dwelling older adults (69.1% women) were assessed for 49 body-size variables (anthropometry, body composition and body indexes), handgrip strength (HGS), one maximum repetition measurement for knee extensors (1RM), isokinetic knee extension peak torque at 60°/s (PT), and six-minute walk test (6MWT).

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Access to dermatological care can be challenging in certain regions of the world. The triage process is usually conducted by primary care physicians; however, they may not be able to diagnose and assign the correct referral and level of priority for different dermatosis. The present research aimed to test different deep neural networks to obtain the highest level of accuracy for the following: (1) diagnosing groups of dermatoses; (2) correct referrals; and (3) the level of priority given to the referral compared to dermatologists.

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Objective: To qualify a 3C approach model of dual-energy X-ray absorptiometry (DXA) to estimate multicomponent resting energy expenditure (REE) referenced by indirect calorimetry (IC).

Methods: A sample of 155 college students, of both sexes (18-30 years old) was evaluated. Anthropometric measures, REE by IC, and whole-body DXA-scans were performed.

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Purpose: Handgrip strength used to identify sarcopenia is not representative of overall strength, especially as greater muscle volume and consequent autonomy-mobility are concentrated in the lower limbs. While absolute strength or relative to body mass is used to define sarcopenia, this relationship is not always linear. The aim of this study was to establish allometrically adjusted cut-off points of lower limb (quadriceps) muscle strength to identify sarcopenia risk in older adults.

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Background: Dynamic knee extensor muscle strength is a valid measure among healthy older adults but has not been tested in the sarcopenia condition. This study's objective was to test the validity of a one-repetition submaximal strength protocol to measure dynamic knee extension strength in older adults with and without sarcopenia.

Methods: Ninety-four physically independent older adults (female:  = 64, 60 to 85 years; male:  = 29, 60 to 85 years) participated in this study in Brazil during 2016-2017.

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Background: Body composition alterations, or lipodystrophy, can lead to serious health problems in people living with HIV/AIDS (PLWHA). The objectives of this study are to predict and validate sex-specific anthropometric predictive models for the diagnosis of lipodystrophy in PLWHA.

Methods: A cross-sectional design was employed to recruit 106 PLWHA (men = 65 and women = 41) in Brazil during 2013-2014.

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Metabolism disorders, as well as body shape abnormalities, have been associated with the introduction of antiretroviral therapy. The objective of this study was to compare the diagnostic ability of adiposity indices and to discuss criteria for the classification of lipodystrophy and sarcopenia (SP) in HIV-positive individuals. Anthropometric measurements were determined in 268 individuals of both genders, also submitted to the dual-energy X-ray absorptiometry exam.

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