Synopsis of recent research by authors named "Andre Minoche"
- Recent research by Andre Minoche emphasizes the application of whole genome sequencing (WGS) in diagnosing complex disorders, such as hepatoblastoma and mitochondrial diseases, highlighting its superiority over traditional techniques like whole exome sequencing (WES) and targeted gene panels.
- His studies reveal significant insights into cancer modeling, particularly in breast cancer, identifying recurrent genomic alterations in both cell lines and patient-derived xenografts, thereby contributing to the understanding of cancer genomics.
- Additionally, Minoche's work spans diverse areas, including the genomic characterization of inherited retinal dystrophies and congenital cataracts, advocating for the broader use of genome sequencing as a diagnostic tool to improve accuracy and treatment outcomes in various genetic conditions.
