Objective: To investigate the role of physical activity in functional and molecular bladder alterations in an obese and insulin-resistant murine model.
Methods: Wistar rats were randomized into 1. physical activity and standard diet; 2.
Purpose:: To analyze the influence of chlorpromazine on renal histology of rats submitted to ischemia and reperfusion injury.
Methods:: Sixteen Wistar rats - split in two groups - have been used: control group, receiving 3 mg/kg isotonic saline solution through caudal vein, and, the chlorpromazine group, receiving 3 mg/kg-IV of such medication. The nephrectomy of the left kidney lower third was carried out; immediately, the test-drug was administrated.