High percentage of immune Th1 and Tc1 cells infiltrating visceral adipose tissue in people with obesity.

Subcutaneous (SAT) and visceral (VAT) adipose tissue dysfunction during the obesity onset can lead to increased expression of inflammatory molecules, and consequently to immune cell infiltration. The aim was to deeply characterize the T cells, those infiltrating SAT and VAT, compared to peripheral blood (PB), in individuals undergoing bariatric surgery. Forty-two adult individuals were recruited, SAT and VAT samples were collected.

Identification and characterization of circulating and adipose tissue infiltrated CD20T cells from subjects with obesity that undergo bariatric surgery.

T cells play critical roles in adipose tissue (AT) inflammation. The role of CD20T cell in AT dysfunction and their contributing to insulin resistance (IR) and type 2 diabetes progression, is not known. The aim was to characterize CD20T cells in omental (OAT), subcutaneous (SAT) and peripheral blood (PB) from subjects with obesity (OB, n = 42), by flow cytometry.

Bariatric Surgery Induces Alterations in the Immune Profile of Peripheral Blood T Cells.

Low-grade inflammation is closely linked to obesity and obesity-related comorbidities; therefore, immune cells have become an important topic in obesity research. Here, we performed a deep phenotypic characterization of circulating T cells in people with obesity, using flow cytometry. Forty-one individuals with obesity (OB) and clinical criteria for bariatric surgery were enrolled in this study.

CD8 Treg cells play a role in the obesity-associated insulin resistance.

Obesity-related chronic low-grade inflammation may trigger insulin resistance and type 2 diabetes (T2D) development. Cells with regulatory phenotype have been shown to be reduced during obesity, especially CD4 Treg cells. However, little is known about the CD8 Treg cells.

Cervical inflammatory mass: a very late complication following neonatal oesophagocoloplasty for oesophageal atresia.

We report the case of a man in his 40s who presented to our emergency department with a history of fever and a red, swollen and painful neck mass. Shortly following his birth, a congenital oesophageal atresia had been managed surgically with colonic interposition graft. Contrast CT of the neck revealed filling and distention of a colic stump with content of stasis and infection.

Transhiatal esophagectomy in Boerhaave syndrome - Case report and literature review.

Introduction: Boerhaave syndrome or spontaneous rupture of the esophagus wall is a rare life-threatening condition. It is more common in male gender and is due to a very swift rise in intraluminal pressure during vomiting. The patient usually presents with chest pain after vomiting.

30-Day Morbidity and Mortality of Bariatric Surgery During the COVID-19 Pandemic: a Multinational Cohort Study of 7704 Patients from 42 Countries.

Background: There are data on the safety of cancer surgery and the efficacy of preventive strategies on the prevention of postoperative symptomatic COVID-19 in these patients. But there is little such data for any elective surgery. The main objectives of this study were to examine the safety of bariatric surgery (BS) during the coronavirus disease 2019 (COVID-19) pandemic and to determine the efficacy of perioperative COVID-19 protective strategies on postoperative symptomatic COVID-19 rates.

Anastomotic fistula after emergency enterectomy for retrograde intussusception after gastric bypass.

Retrograde intussusception is a rare complication of gastric bypass. It is commonly located in the common limb close to the jejunojejunostomy. The management of such condition dictates the outcome of the patient either in the immediate emergency setting or in the long-term bariatric surgery's expected results.

Femoral Hernia Containing the Right Fallopian Tube: A Rare Finding.

Femoral hernias comprise a small proportion of all groin hernias. They are more common in women and have a high rate of incarceration and strangulation, leading to emergency repair. A 61-year-old female patient was admitted to the emergency department complaining of a 2-day painful lump in the right groin, that had become more intense in the last 24 hours.