Physician, heal thyself: Survey of users of the Quebec Physicians Health Program.

Objective: To document the opinions of the users of the Quebec Physicians Health Program (QPHP) about the services they received.

Design: Mailed questionnaire.

Setting: Quebec.

Relaying asymmetry of transient atropisomers of o-iodoanilides by radical cyclizations.

Atropisomers of N-2 degrees -alkyl-N-acryloyl-2-iodoanlides have been resolved by chromatography and crystallization-induced asymmetric transformation. These molecules have atropisomerization barriers of 23-24 kcal/mol and return to equilibrium ratios over several hours at ambient temperature in solution. The transient chirality can be locked in by radical cyclizations, which provide N-2 degrees -alkyl-3-methyl-1,3-dihydroindol-2-ones with high levels of chirality transfer.