Publications by authors named "Andre L Lopes Saraiva"
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Synopsis of recent research by authors named "Andre L Lopes Saraiva"
- Andre L Lopes Saraiva's recent research focuses on the therapeutic potential of angiotensin type 2 receptor antagonism as a novel strategy for managing gout, particularly in the context of acute attacks.
- The study employed a mouse model to assess the analgesic and anti-inflammatory effects of the ATR antagonist PD123319 compared to vehicle injections in the presence of monosodium urate crystals, simulating an acute gout scenario.
- The findings indicate that blockade of the angiotensin type 2 receptor may alleviate symptoms associated with gout attacks, such as pain sensitivity and swelling, highlighting its potential as a new treatment avenue for this condition.