Detecting the effect of Alzheimer's disease on everyday motion behavior.

Background: Early detection of behavioral changes in Alzheimer's disease (AD) would help the design and implementation of specific interventions.

Objective: The target of our investigation was to establish a correlation between diagnosis and unconstrained motion behavior in subjects without major clinical behavior impairments.

Method: We studied everyday motion behavior in 23 dyads with one partner suffering from AD dementia and one cognitively healthy partner in the subjects' home, employing ankle-mounted three-axes accelerometric sensors.

Identification of determinants for weight reduction in overweight and obese children and adolescents.

We conducted a pilot trial of electronic technology integrated into the treatment of children and adolescents who are overweight or obese. A total of 30 patients (mean age 14 years, mean BMI 32.7 kg/m(2)) were admitted to our hospital to participate in a structured treatment and teaching programme (STTP).