Hospital Venous Thromboembolism Prevention: A Year-Long Case Based Caprini Score Risk Analysis with Findings Suggesting Optimal Care.

Introduction: Venous thromboembolism (VTE) is a common cause of hospital morbidity and mortality. VTE risk assessment can provide a reduction in these events if optimal prophylactic interventions are taken. The Caprini Risk Assessment (CRA) score is a validated VTE risk scoring system available for hospitalized patient risk stratification.

Acute Liver Failure With Severe Lactic Acidosis Secondary to Infiltrative Diffuse Large B-Cell Lymphoma: An Imaging-Negative Presentation.

Liver involvement by non-Hodgkin's lymphoma is common in late stage disease but rarely results in severe hepatic dysfunction. Here, we discuss a case of acute liver failure (ALF) with severe lactic acidosis in a 75-year-old female with diffuse large B-cell lymphoma (DLBCL). The patient was admitted with nausea, fevers, and mild acidosis.

UBXN2A enhances CHIP-mediated proteasomal degradation of oncoprotein mortalin-2 in cancer cells.

Overexpression of oncoproteins is a major cause of treatment failure using current chemotherapeutic drugs. Drug-induced degradation of oncoproteins is feasible and can improve clinical outcomes in diverse types of cancers. Mortalin-2 (mot-2) is a dominant oncoprotein in several tumors, including colorectal cancer (CRC).