Publications by authors named "Andre Felipe Nahoum"
Single-dose pharmacokinetics and pharmacodynamics assessment of oestriol and trimegestone containing vaginal rings in healthy women with childbearing potential.
Natalícia de Jesus Antunes Raimundo Vieira de Oliveira Filho Jaime de Oliveira Ilha Ronilson A Moreno André Felipe Nahoum
Eur J Contracept Reprod Health Care
June 2021
Article Synopsis
- - The study aimed to analyze how well oestriol (E3) and trimegestone (TMG) are absorbed and work in the body when delivered via three different vaginal rings over 21 days, each with varying doses of E3/TMG.
- - Thirty-five healthy women participated, receiving one of the three test rings, while blood samples measured hormone levels and safety was monitored through adverse events.
- - Results showed that the third test ring provided the best balance of E3/TMG for preventing bleeding and achieving contraception, with all rings being well tolerated by participants.