Publications by authors named "Andre Abela"
Neurobiol Aging
March 2023
Article Synopsis
- The study examines the genetic and clinical profiles of the largest group of ALS patients from Malta, highlighting the island's unique genetic isolate status.
- Using whole-genome sequencing, researchers found that over 45% of patients had damaging genetic variants associated with ALS, primarily in less common genes like ALS2 and SETX.
- Importantly, major ALS-related genes were rarely found in Maltese patients, suggesting that Malta’s population presents a distinct genetic landscape for understanding ALS risk factors.
