Publications by authors named "Andre A Dos Santos"
Article Synopsis
- - Candida albicans is the main cause of oral candidiasis, and its growing resistance to drugs has sparked the search for better antifungal treatments, leading researchers to investigate the effects of (-)-fenchone.
- - The study found that (-)-fenchone is effective against C. albicans, including strains resistant to miconazole, demonstrating strong antifungal properties with a Minimum Inhibitory Concentration (MIC) of 8 μg/mL.
- - Negative effects on the fungus do not stem from cell wall or membrane damage, and although (-)-fenchone has some ability to prevent biofilm formation, it doesn't disrupt existing biofilms; it also showed low toxicity, suggesting it could be a viable treatment
The plant species L. is a staple in cuisine and holds significant ethnopharmacological value. Its essential oil (EO) is of particular interest, yet its toxicity profile remains a subject of inquiry.
View Article and Find Full Text PDFCancer, the second leading global cause of death, impacts both physically and emotionally. Conventional treatments such as surgeries, chemotherapy, and radiotherapy have adverse effects, driving the need for more precise approaches. Precision medicine enables more targeted treatments.
View Article and Find Full Text PDFVitamins are organic compounds present in low concentrations in food, performing vital and specific cell metabolism functions. Vitamin B12 is essential for red blood cell formation in the bone marrow and its deficiency is caused, mainly, by gastrointestinal malabsorption. In addition to systemic manifestations, oral signs and symptoms have also been associated to this condition such as glossitis, papillary atrophy, painful erythema areas, burning sensation, dysgeusia, lingual paresthesia and itching.
View Article and Find Full Text PDF