Publications by authors named "Andjela Baewert"
Article Synopsis
- The study investigates racial bias among medical students towards immigrants by assessing their willingness to administer pain medication to patients of varying immigrant statuses.
- Conducted as a randomized control trial, second-year medical students were shown videos of patients (male or female) and asked if they would provide pain relief.
- Results indicated that while 95% of students administered pain medication regardless of immigrant status, immigrants were less likely to receive high-potency analgesia, and female students were more likely to give medication and rated patient pain higher than their male counterparts.
Objectives: Lessons learned in research and treatment of opioid dependence demonstrate the need to include pregnant women in clinical trials.
Methods: Two double-blind, double-dummy, randomized controlled trials (Pilot study, European sample(†) of MOTHER-trial) comparing buprenorphine and methadone in opioid-dependent pregnant women were conducted. In both studies, participants received voucher-based incentives for attendance and completion of study assessments.
Aims: This paper reviews the published literature regarding outcomes following maternal treatment with buprenorphine in five areas: maternal efficacy, fetal effects, neonatal effects, effects on breast milk and longer-term developmental effects.
Methods: Within each outcome area, findings are summarized first for the three randomized clinical trials and then for the 44 non-randomized studies (i.e.
Background: Multi-center trials enable the recruitment of larger study samples, although results might be influenced by site-specific factors.
Methods: Site differences of a multi-center prospective double-blind, double-dummy randomized controlled trial (7 centers: Central Europe (Vienna)/USA (3 urban/3 rural centers)) comparing safety and efficacy of methadone and buprenorphine in pregnant opioid-dependent women and their neonates.
Results: Urban US women had the highest rate of concomitant opioid (p = 0.
Background: Prenatal nicotine exposure is associated with increased neonatal mortality, low birth weight, and smaller head circumference. Opioid-dependent pregnant women show a particularly high prevalence of tobacco smoking and are at greater risk for additional adverse events. However, little is known about the impact of tobacco smoking on opioid-maintained pregnant women and neonatal outcomes.
View Article and Find Full Text PDFTo evaluate driving aptitude and traffic-relevant performance at peak and trough medication levels in opioid-dependent patients receiving maintenance therapy with either buprenorphine (mean: 13.4 mg) or methadone (52.7 mg) and a medication-free control group, the Addiction Clinic at Medical University Vienna conducted a prospective, open-label trial where 40 opioid-dependent patients maintained either on buprenorphine or methadone were assessed regarding their traffic-relevant performance.
View Article and Find Full Text PDFNeonates born to opioid-maintained mothers are at risk of developing neonatal abstinence syndrome (NAS), which often requires pharmacological treatment. This study examined the effect of opioid maintenance treatment on the incidence and timing of NAS, and compared two different NAS treatments (phenobarbital versus morphine hydrochloride). Fifty-three neonates born to opioid-maintained mothers were included in this study.
View Article and Find Full Text PDFArticle Synopsis
- - The study aimed to compare the effectiveness and safety of methadone versus buprenorphine for treating opioid-dependent pregnant women, conducted at a clinic in Vienna with 18 participants.
- - Participants were randomly assigned to receive either methadone or buprenorphine, and results indicated better retention rates in the buprenorphine group while the methadone group experienced less concurrent opioid use.
- - Findings suggested that neonates exposed to methadone had an earlier onset of neonatal abstinence syndrome (NAS) compared to those exposed to buprenorphine, highlighting the need for further research in this area.