Publications by authors named "Andi D Putra"

Radioresistance poses a significant challenge in the effective treatment of cervical cancer, often leading to poor patient outcomes. MicroRNA-21 (miR-21) and MicroRNA-145 (miR-145) are oncogenic micro-RNAs associated with various cancers, including cervical cancer, but their potential as predictive biomarkers for radioresistance remains underexplored. This study aimed to investigate the association between miR-21 and miR-145 expressions and the response to radiation therapy in cervical cancer patients.

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Objective: Ovarian cancer is one of the most common cancers with a high mortality rate worldwide. Despite optimal surgical therapy and chemotherapy, recurrence is still common. Cancer stem cells expressing CD44 and CD24 are thought to be contributing factors in recurrence.

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Article Synopsis
  • The study explored the link between insulin resistance (IR) and ovarian neoplasms, focusing on differences in characteristics and IR prevalence between benign and malignant cases in 52 non-diabetic women.
  • Findings showed that women with benign neoplasms were younger and generally had a higher body mass index (BMI) compared to those with malignant neoplasms.
  • Despite differences in clinical features and indicators of β-cell dysfunction, the overall prevalence of insulin resistance did not significantly differ between the two groups.
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Early detection and treatment of cervical intraepithelial neoplasia (CIN) through a "see and treat" approach is a pillar of cervical cancer prevention programs in developing countries such as Indonesia. One of the major challenges faced is the limited NO or CO gas supply for cryotherapy. Thus, an alternative therapeutic method such as trichloroacetic acid (TCA) topical application is needed as an alternative solution.

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Uterine leiomyosarcoma is a rare malignancy and is difficult to diagnose preoperatively. In this case series, we retrospectively reassessed ultrasound findings of 18 leiomyosarcoma cases and proposed the diagnostic workup. We are select seven ultrasound features and found irregular tumor border in 100%, loss of normal myometrium >25% in 61.

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Article Synopsis
  • Peritoneal Tuberculosis (PTB) is a rare form of extrapulmonary TB affecting 1-2% of patients, more common in developing countries, and can be mistaken for advanced ovarian cancer, making accurate diagnosis crucial.
  • A 36-year-old woman presented with abdominal symptoms and elevated CA 125 levels, leading to a differential diagnosis that included PTB; diagnostic laparoscopy confirmed PTB without malignancy signs.
  • Laparoscopy is highlighted as the most effective method for distinguishing PTB from other serious conditions like peritoneal carcinomatosis and advanced ovarian cancer, allowing for direct observation and biopsy.
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Introduction: Metastases in cervical cancer could be spread through direct local invasion, lymphatic dissemination, or hematogenous dissemination. The most common sites of distant metastases are lungs, bone, and liver. Skin metastases from cervical cancer are categorized as a rare occurrence of metastases.

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