Publications by authors named "Anders Kirstein Pedersen"
DDD(R)-pacing, but not AAI(R)-pacing induces left ventricular desynchronization in patients with sick sinus syndrome: tissue-Doppler and 3D echocardiographic evaluation in a randomized controlled comparison.
Europace
February 2008
Article Synopsis
- The study investigates the effects of right ventricular (RV) pacing on heart function in 50 patients with sick sinus syndrome, comparing atrial pacing (AAI(R)) and dual chamber RV-pacing (DDD(R)).
- Results showed that DDD(R)-pacing resulted in increased left ventricular (LV) dyssynchrony and a significant decrease in LV ejection fraction (LVEF) over 12 months, while AAI(R)-pacing did not show these changes.
- The conclusion emphasizes that DDD(R)-pacing leads to notable LV desynchronization and decline in heart function, which is not seen with AAI(R)-pacing in these patients.
Article Synopsis
- The study compares two main methods of radiofrequency ablation for treating atrial fibrillation: segmental pulmonary vein isolation (SPVI) and circumferential pulmonary vein isolation (CPVI).
- Results show that 73% of patients were symptom-free after CPVI, while only 25% were symptom-free after SPVI.
- The findings suggest that CPVI is a safer and more effective treatment for patients with severe symptoms and drug-resistant AF when performed by experienced specialists.
The aim of this study was to evaluate whether the incidence of ventricular arrhythmias and heart rate variability were influenced by statin treatment and lipid levels in patients treated with an implantable cardioverter defibrillator (ICD). Heart rate variability measurements were performed in 86 patients with coronary heart disease and an ICD implant. The number of events with ventricular fibrillation and ventricular tachycardia were recorded during a 12-month period.
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- The study focuses on the effectiveness of cardiac resynchronization therapy (CRT) using left ventricular (LV) pacing in patients with severe heart failure, analyzing the impact of different anatomic locations for LV lead placement.
- A total of 120 patients were successfully implanted with LV leads, showing a significant reduction in implantation time over the study period and stable lead performance during follow-up, although the stimulation threshold increased slightly.
- Results indicated no major differences in LV lead performance based on the pacing site, with phrenic nerve stimulation occurring more frequently in one specific group, highlighting the importance of training for successful LV lead implantation.
Aim: To investigate the relationship between serum content of n-3 polyunsaturated fatty acids (PUFA) and the incidence of ventricular arrhythmias in patients with an implantable cardioverter defibrillator (ICD).
Methods: We included 98 patients with ischaemic heart disease and an ICD. The numbers of ventricular fibrillation (VF) and ventricular tachycardia (VT) events were assessed during a 12-month period and related to the concentration of n-3 PUFA in serum phospholipids.
Article Synopsis
- * Researchers analyzed 36 patients who were resistant to antiarrhythmic drugs, using advanced mapping and pacing techniques to target specific reentrant circuits for radiofrequency (RF) ablation.
- * Results showed a high success rate (94% for targeted tachycardias) with minimal complications, indicating that modern ablation techniques are effective and safe for these patients.
Aim: The aim of the present study was to validate pacemaker telemetry as a diagnostic feature for detecting atrial tachyarrhythmias (AT) during pacemaker treatment in patients with sick sinus syndrome (SSS).
Methods And Results: Patients with SSS and bradytachy syndrome (n = 28, 20 women), mean age 71 +/- 10.3 years, were included.
Sinus and paced P wave duration and dispersion as predictors of atrial fibrillation after pacemaker implantation in patients with isolated sick sinus syndrome.
Pacing Clin Electrophysiol
May 2004
The aim of this study was to prospectively evaluate the sinus and the paced P wave duration and dispersion as predictors of AF after pacemaker implantation in patients with isolated sick sinus syndrome (SSS). The study included 109 (69 women, mean age 72 +/- 11 years) patients with SSS, 59 with bradycardia-tachycardia syndrome (BTS). A 12-lead ECG was recorded before pacemaker implantation and during high right atrial and septal right atrial pacing at 70 and 100 beats/min.
View Article and Find Full Text PDFRegional myocardial perfusion during chronic biventricular pacing and after acute change of the pacing mode in patients with congestive heart failure and bundle branch block treated with an atrioventricular sequential biventricular pacemaker.
Eur J Heart Fail
March 2003
Background: Biventricular (BiV) pacing has been found to improve systolic function and exercise tolerance in patients with severe congestive heart failure and bundle branch block. The mechanisms behind this beneficial effect is still not sufficiently clarified.
Aim: To evaluate the regional myocardial perfusion (MP) during BiV pacing and after acute change of the pacing mode to conventional dual chamber (DDD) pacing, and single chamber atrial (AAI) pacing in patients with severe congestive heart failure and prolonged QRS width treated with chronic BiV pacing.
Background: recent short-term observations have shown an improvement in cardiac function and heart failure symptoms from atrio-biventricular pacing. This study was designed to assess the safety and feasibility of an atrio-biventricular transvenous pacing system, and examine the long-term effects of cardiac resynchronization in patients with advanced heart failure and ventricular conduction abnormalities.
Methods And Results: between August, 1997 and November, 1998, 103 patients received a cardiac resynchronization system (CRS) consisting of a pulse generator interfaced with an atrio-biventricular lead system, including a lead designed for left ventricular (LV) pacing via cardiac veins.
The prognostic accuracy of different QT interval measures.
Ann Noninvasive Electrocardiol
January 2002
Background: The QT intervals accuracy for predicting arrhythmic death varies between studies, possibly due to differences in the selection of the lead used for measurement of the QT interval. The purpose of this study was to analyze the prognostic accuracy of all known ways to select the lead.
Methods And Results: Three institutions that used different methods for measuring QT intervals provided their QT databases.
Weighing the QT intervals with the slope or the amplitude of the T wave.
Ann Noninvasive Electrocardiol
January 2002
Objective: The reproducibility of QT interval measurements is low, even for the mean QT interval based on the standard ECG. In this study we analyzed whether the reproducibility of the mean weighed QT interval was better than the simple mean QT interval. The weighing was based on the amplitude of the T wave or the slope of the steepest tangent on the terminal part of the T wave.
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