Publications by authors named "Anders Gravholt"
Introduction: Cerebral palsy (CP) presents a complex neurodevelopmental disorder with a spectrum of motor impairments stemming from early brain injury. Whereas CP is traditionally viewed as a non-progressive condition, emerging evidence suggests a progressive decline in mobility and function, particularly in adulthood. Despite the prevalence of self-reported age-related gait decline in adults with CP, objective evidence supporting this phenomenon remains limited.
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- * This review aims to provide evidence of the decline in motor function and gait in aging adults with CP and to explore potential reasons behind these changes, highlighting that this aspect has been less studied compared to comparisons with typically developing individuals.
- * Factors like comorbid diagnoses and changes in the neuromuscular and cardiovascular systems may accelerate mobility issues in those with CP, suggesting that future research is needed to improve understanding and develop strategies to enhance the quality of
Introduction/purpose: Recently, the use of transcutaneous spinal cord stimulation (TSCS) has been proposed as a viable alternative to the H-reflex. The aim of the current study was to investigate to what extent the two modes of spinal cord excitability investigation would be similarly sensitive to the well-known vibration-induced depression.
Methods: Fourteen healthy participants (8 men and 6 women; age: 26.
The effect of low-frequency fatigue on the torque-velocity relationship in human quadriceps.
J Appl Physiol (1985)
December 2023
Article Synopsis
- Low-frequency fatigue (LFF) is characterized by a decrease in the ability of muscles to generate force at low frequencies compared to high frequencies during electrical stimulation.
- In a study with 16 participants, knee extensions were performed to measure how LFF affected the torque-velocity relationship after inducing fatigue through dynamic exercises.
- Results showed that maximal torque and power significantly decreased after fatigue, while the maximal contraction velocity remained largely unchanged, suggesting that LFF affects muscle power production but not contraction speed during low- and high-frequency exercise.
Objective: To investigate (1) how current and pulse frequency of electrical stimulation (ES) as well as contraction mode (isometric, concentric, and eccentric) influence torque output and discomfort and (2) how familiarization by repeated ES sessions influences ratings of perceived discomfort.
Design: An experimental study, 3 sessions.
Setting: A university laboratory.
Ischemic conditioning and exercise have been suggested for protecting against brain ischemia-reperfusion injury. However, the endogenous protective mechanisms stimulated by these interventions remain unclear. Here, in a comprehensive translational study, we investigated the protective role of extracellular vesicles (EVs) released after remote ischemic conditioning (RIC), blood flow restricted resistance exercise (BFRRE), or high-load resistance exercise (HLRE).
View Article and Find Full Text PDFHigh-load resistance exercise contributes to maintenance of muscle mass, muscle protein quality, and contractile function by stimulation of muscle protein synthesis (MPS), hypertrophy, and strength gains. However, high loading may not be feasible in several clinical populations. Low-load blood flow restricted resistance exercise (BFRRE) may provide an alternative approach.
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