Publications by authors named "Anders Boesen"

Elongation of the tendon has been proposed as the most important factor leading to poor outcome after acute Achilles tendon rupture (ATR). The aim of this paper was to investigate if Amlang's ultrasound classification (AmC) or the Copenhagen Achilles Length Measurement (CALM) when assessed in the acute phase after ATR could predict elongation 1 y after rupture. 107 males and 27 females, aged 18 to 70 y and treated nonsurgically were included.

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Introduction: Achilles tendinopathy (AT) is a common and disabling musculoskeletal condition. First-line management involving Achilles tendon loading exercise with, or without, other modalities may not resolve the problem in up to 44% of cases. Many people receive injections.

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  • - The study aimed to explore the effects of six weeks of intensive ballet training on the Achilles tendon in terms of structural and clinical changes, and to analyze factors like demographics, self-reported pain, and generalized joint hypermobility (GJH).
  • - Results showed a significant decrease in the healthy echo-type I (indicating tendon integrity) and an increase in echo-type II (suggesting changes in tendon structure), particularly affected by limb and sex differences among the 63 ballet dancers aged 18-41.
  • - Despite these structural changes in the Achilles tendon after rehearsing for Swan Lake, there were no notable changes in self-reported symptoms, clinical signs of Achilles tendinopathy, or performance in heel raise tests during
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Background: An acute Achilles tendon rupture (ATR) is a long-lasting and devastating injury. Possible biological augmentation to promote and strengthen tendon healing after an ATR would be desirable.

Purpose: To determine whether the application of a platelet-rich plasma (PRP) injection in nonsurgically treated ATRs may promote healing and thereby improve functional outcomes.

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  • High volume injection (HVI) is effective for treating chronic midportion Achilles tendinopathy (AT), with studies showing better short-term outcomes with corticosteroid added to the injection.
  • A clinical trial involving 28 men demonstrated that those receiving HVI with corticosteroid experienced greater improvements in pain and function scores at 6 and 12 weeks compared to those without corticosteroid.
  • Both treatment groups showed tendon thickness reduction over time, but the corticosteroid group had more significant results at 6 and 12 weeks, suggesting that corticosteroids may enhance the short-term effectiveness of HVI.
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Purpose: The discovery of musculoskeletal tissues, including muscle, tendons, and cartilage, as peripheral circadian clocks strongly implicates their role in tissue-specific homeostasis. Age-related dampening and misalignment of the tendon circadian rhythm and its outputs may be responsible for the decline in tendon homeostasis. It is unknown which entrainment signals are responsible for the synchronization of the tendon clock to the light-dark cycle.

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Tendinopathy is a condition of tendon overuse and is a very common cause of morbidity among recreational and competitive athletes. Chronic overload results in degenerative changes of the tendon, which becomes painful and swollen with impaired function. A reduction in the overloading activity is the mainstay of the treatment.

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Introduction: Valid length measurements of the different segments of the Achilles tendon are needed in order to investigate if differential elongation of the Achilles tendon takes place after rupture. The purpose of this paper was to present data concerning the accuracy and reliability of an ultrasound measurement of the free part of the Achilles tendon.

Methods: Both legs of 19 non-injured subjects were examined by magnetic resonance imagining (MRI) and ultrasound.

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The menisci play a major role in knee function regarding joint movement, stability, load distribution and load transmission. Injuries to the menisci cause pain, and meniscal tears are a common reason for patient referral. In Denmark, partial meniscectomy increased significantly until 2010, and several studies have questioned the long-term effect of meniscectomy as an overall procedure.

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Background: Injection therapies are often considered alongside exercise for chronic midportion Achilles tendinopathy (AT), although evidence of their efficacy is sparse.

Purpose: To determine whether eccentric training in combination with high-volume injection (HVI) or platelet-rich plasma (PRP) injections improves outcomes in AT.

Study Design: Randomized controlled trial; Level of evidence, 1.

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  • Nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen are used for pain relief during periods of inactivity, but their effects on tendon health in elderly individuals are unclear.
  • In a study involving 19 men aged 60-80, researchers investigated tendon collagen synthesis and mechanical properties after 2 weeks of immobilization and 6 weeks of rehabilitation with and without NSAID treatment.
  • The results showed a significant decrease in collagen protein synthesis due to immobilization, but tendon stiffness and mechanical properties were only slightly affected, indicating that mechanical loading is crucial for maintaining tendon health despite short-term inactivity.
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  • The study compared Achilles tendon stiffness and plantar pressure in poorly and well-controlled diabetic patients with healthy controls, finding no differences between the two diabetes groups.
  • It was revealed that diabetic patients had significantly greater collagen cross-linking and tendon stiffness compared to controls, along with a higher forefoot/rearfoot peak-plantar-pressure ratio, potentially contributing to foot ulcer development.
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Introduction: Recent studies have shown that vitamin-D intake can improve skeletal muscle function and strength in frail vitamin-D insufficient individuals. We investigated whether vitamin-D intake can improve the muscular response to resistance training in healthy young and elderly individuals, respectively.

Methods: Healthy untrained young (n = 20, age 20-30) and elderly (n = 20, age 60-75) men were randomized to 16 weeks of daily supplementary intake of either 48 μg of vitamin-D + 800 mg calcium (Vitamin-D-group) or 800 mg calcium (Placebo-group) during a period and at a latitude of low sunlight (December-April, 56°N).

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Introduction: Rheumatoid arthritis (RA) is often associated with diminished muscle mass, reflecting an imbalance between protein synthesis and protein breakdown. To investigate the anabolic potential of both exercise and nutritional protein intake we investigated the muscle protein synthesis rate and anabolic signaling response in patients with RA compared to healthy controls.

Methods: Thirteen RA patients (age range 34-84 years; diagnosed for 1-32 years, median 8 years) were individually matched with 13 healthy controls for gender, age, BMI and activity level (CON).

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Purpose: A clinically applicable and accurate method for measuring Achilles tendon length is needed to investigate the influence of elongation of the Achilles tendon after acute rupture. The purpose of this study was to develop and validate an ultrasonographic (US) length measurement of the Achilles tendon-aponeurosis complex.

Methods: Both legs of 19 non-injured subjects were examined by magnetic resonance imaging (MRI) and US.

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The best treatment of acute Achilles tendon rupture has been discussed for decades. During the past half decade, evidence has increased in favor of nonoperative treatment and dynamic and weightbearing rehabilitation. We hypothesized that the treatment strategies would show great variation and that adherence to evidence-based recommendations would not be as good as desired.

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Background: Color Doppler ultrasound is widely used to examine intratendinous flow in individuals with overuse tendon problems, but the association between color Doppler and pain is still unclear.

Hypothesis: Intratendinous flow is present and associated with pain in badminton players, and intratendinous flow and pain increase during a badminton season.

Study Design: Cohort study (prognosis); Level of evidence, 2.

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Tendon-related injuries are a major problem, but the aetiology of tendinopathies is unknown. In tendinopathies as well as during unaccustomed loading, intra-tendinous flow can be detected indicating that extensive loading can provoke intra-tendinous flow. The aim of present study is to evaluate the vascular response as indicated by colour Doppler (CD) activity in both the Achilles and patella tendon after loading during high-level badminton matches.

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Background: The most frequent injuries in badminton players are in the lower extremities, especially in the Achilles tendon.

Hypothesis: The game of badminton may be related to abnormal intratendinous flow in the Achilles tendon as detected by color Doppler ultrasound. To a certain extent, this blood flow might be physiological, especially when examined after match.

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