Publications by authors named "Anda Gonciulea"
Background: Proteinuria has been associated with bone loss and fractures in general population, but data in HIV-infected population are lacking.
Setting: Prospective, multicenter cohort study of men with or at risk of HIV infection.
Methods: Between 2006 and 2015, urine protein measurements and bone fracture histories were ascertained semiannually in 947 HIV-infected (HIV+) and 969 HIV-uninfected (HIV-) men aged 40 years or older.
Objectives: To determine the incidence of fracture among aging HIV-infected (HIV+) and uninfected men (HIV-). To evaluate factors independently associated with fracture risk.
Design: Prospective, multicenter cohort study of men with or at risk for HIV.
Background: Plant-based diets can lower serum lipids. Whether soy foods offer additional benefits remains controversial.
Objective: To determine the effect of different protein sources on serum lipids and glucose metabolism, emphasizing comparisons between soy and nonsoy plant-based diets.
Article Synopsis
- - FGF23 is a key player in managing phosphate and vitamin D levels in the body, and imbalances in its production can lead to various bone diseases.
- - The article focuses on the FGF23-α-Klotho signaling pathway, providing an overview of recent advancements in understanding how FGF23 is regulated and how it functions.
- - It also discusses the health issues connected to either too much or too little FGF23, outlining the disorders that arise from these imbalances.
Article Synopsis
- The skeleton is recognized not just for movement and calcium regulation but also as an active endocrine organ, influencing various bodily functions.
- Key processes like bone remodeling involve complex interactions between different bone cells and various signaling pathways, such as Wnt/β catenin and FGF23.
- The review highlights how these pathways affect human bone disorders and their potential for developing new diagnostic and treatment methods.