Toward tunable amphiphilic copolymers via CuAAC click chemistry of oligocaprolactones onto starch backbone.

Starch-based tunable amphiphilic copolymers are easily obtained by grafting polycaprolactone chains via 1,3 dipolar Copper-Catalyzed Azide-Alkyne Cycloaddition (click chemistry CuAAC), starting from propargylated starch and azido oligocaprolactones with different chain lengths as the precursors. The copolymers are characterized by (1)H and (13)C NMR, from which a degree of substitution of starch can tentatively be deduced. Besides these bulk characterizations, the surface of the functionalized starch is also characterized by XPS which confirms the triazole formation, particularly through the deconvolution of the N 1s peak, and by ToF-SIMS which, not only confirms the surface modification, but also highlights the disappearance of the Cu(+) cations.