Publications by authors named "Anca Toiu"

Nowadays, there is an increasing interest in the study of medicinal and aromatic plants, due to their therapeutic properties that correlate with the presence of different active compounds. species (sp.) are aromatic plants that belong to the Lamiaceae family, originating from North America and East Asia.

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Article Synopsis
  • Hairy willowherb (EH) is a plant native to Europe and Asia, known for its use in folk medicine in Romania, where it includes 17 species.
  • This study explored EH's anti-inflammatory properties using Wistar rats and found that its optimized extract had effects similar to indomethacin, a common anti-inflammatory drug.
  • The research also tested EH's antitumor effects on Swiss albino mice with a specific type of cancer, showing the extract reduced tumor-related inflammation and markers of oxidative stress, suggesting its potential as a natural therapeutic option.
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The genus is part of the family and is native to North America, while one species, (), is native to East Asia. A review on the phytochemistry and bioactivity of genus was last performed in 2014. Since then, a lot of progress has been made on the characterization of the phytochemical and pharmacological profiles of species.

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The present research investigated the in vivo anti-inflammatory and cardioprotective activities, as well as the antioxidant potential of tincture (TOT), in relation to the polyphenolic composition. Chromatographic and spectrophotometric techniques were used to determine the polyphenolic profile of TOT and the antioxidant activity was preliminarily assessed in vitro by DPPH• and FRAP spectrophotometric methods. The in vivo anti-inflammatory and cardioprotective activities were studied in rat turpentine-induced inflammation and in rat isoprenaline-induced myocardial infarction (MI) models.

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  • Romanian folk medicine utilizes endemic plant species for treating benign prostate hyperplasia (BPH), yet there's limited scientific evidence on their effectiveness.
  • This research focused on evaluating the phytochemical properties of five endemic plant species and assessing their biological activities using optimized extraction techniques.
  • Findings revealed strong antioxidant properties, notable antimicrobial effects against certain bacteria, and significant anti-cancer and anti-inflammatory potential in extracts, particularly from the aerial parts of the plants.
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species are often used in traditional medicine as anti-inflammatory, diuretic, wound-healing and antimicrobial agents. Still, the bioactive compounds and biological activities of some species have not been studied. The present work aimed to investigate the polyphenolic profile and the biological properties of L.

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species have been used in traditional medicine for their diuretic, anti-inflammatory, wound-healing, and hepatoprotective properties. The phytochemical profile and anticancer potential of three sp. (, and ) from Romania was investigated.

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Several species are used in Romanian folk medicine for their antioxidant, antimicrobial and anti-inflammatory properties, to treat pain, fever or arthritis. Still, the active compounds responsible for these effects and their mechanism of action are scarcely known. This research was designed to investigate the phytochemical profile (e.

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This study describes an innovative near-infrared (NIR) process monitoring method for the quantification of the total polyphenolic content (TPC) of dry extracts. The dry extract was obtained in a fluidized bed processor, by spraying and adsorbing a liquid extract onto an inert powder support. NIR spectra were recorded continuously during the extract's spraying process.

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In the Romanian folk medicine, aerial parts of ("nobleman's beard," Romanian - "barba boierului" or "avrămească" or "creştinească") are traditionally used as galactagogue and anti-inflammatory agents. The present study aimed to evaluate the chemical composition (polyphenols, iridoids, and phytosterols), antioxidant, antimicrobial and anti-inflammatory activity of different extracts of aerial parts. The major identified bioactive compounds were rutin, 8--acetylharpagide and β-sitosterol.

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Saponins from defatted root-extract of Securidaca longipedunculata were systematically entrapped in emulsion monolayer-barrier and finally recovered in pure form through demulsification. First, their molecules were dispersed in water to engineer a monomolecular film architecture, via self-assembly. Emulsifying with ethyl-ether resulted in swollen micelles and engendered phase-inversion and phase-separation, by disrupting the thermodynamic equilibrium.

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The purpose of this work was to evaluate chemical constituents, antioxidant and antimicrobial activities of Artabotrys hildebrandtii, an endemic medicinal plant from Madagascar. Ethanol extracts from the leaves and stem bark were tested to evaluate DPPH free radical scavenging, using butylated hydroxytoluene and quercetin as standard antioxidants. An high-performance liquid chromatography/mass spectrometry method was developed to investigate the presence of phenolic compounds in the studied samples; gentisic acid, chlorogenic acid, hyperoside, isoquercitrin, rutin, quercitrin, quercetol, apigenin and luteolin were identified.

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The aim of this paper was to evaluate the antioxidant and antimicrobial activities and the polyphenolic content of Schisandra chinensis (Turcz.) Baill. leaves and fruits.

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The aim of this work was to study the chemical composition of Allium obliquum L., A. senescens L.

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Unlabelled: The quantitative and qualitative analysis of essential oils obtained from Salvia officinalis L. (Lamiaceae) cultivated in Romania is reported in this paper.

Material And Methods: The essential oils were obtained from fresh and dried material harvested from plants cultivated in Cluj (Romania) and from 2 commercial samples, by hydrodistillation.

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Unlabelled: In this study we analyzed the chemical composition and we evaluated the diuretic activity of aerial parts of V. tricolor L.

Material And Methods: For saponins and mucilages we have performed gravimetric methods, whereas for carotenoids, spectrophotometric determinations and HPLC analysis were performed.

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Unlabelled: Our study investigated the effects of Ocimum basilicum L. tincture (1:10) in acute inflammation induced with turpentine oil (i.m.

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Aim: Evaluation of anti-inflammatory actions of Viola tricolor aerial parts tincture.

Material And Method: The anti-inflammatory activity of the tincture from Viola tricolor aerial parts was tested in acute inflammation induced with oil of turpentine (i.m.

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Unlabelled: The aim of this study was to investigate the effects of Salvia officinalis L. tincture on acute inflammation induced with oil of turpentine.

Materials And Methods: Oil of turpentine (i.

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