[Primary juvenile glaucoma--clinical and genetic aspects].

Purpose: We have done a retrospective study of juvenile glaucoma cases hospitalized between 1993-2002.

Material And Method: 52 primary juvenile glaucoma patients were available for our clinical and genealogical investigations.

Results: In this study we have analyzed the distribution of cases per year, the age of appearance of the diseases, and the distribution in function of the sex and the genealogical factors.

[Congenital grouped pigmentation of the retina].

A case of grouped pigmentation of the retina with unilateral localisation is presented. The positive diagnosis of this congenital abnormality is decided upon the aspects of the retinal grouped pigmentations and it is confirmed using additional test: angiography, electrophysiological methods, visual field test and adaptometry.

[Humoral and cellular immunity investigation in idiopathic uveitis].

Objectives: There is an amount of controversy regarding the patho-physiology of uveitis. Due to the fact that the eye (and especially the highly vascular tissues such as the uvea and the conjunctiva) is considered a special "target" for the immunopathologic reactions, the goal of our study is to contribute to the understanding of the causal role of the immune reactions in the development of idiopathic uveitis.

Material And Methods: We have studied 48 patients with idiopathic uveitis and 20 control subjects (with no ocular symptomatology) for the following humoral and cellular immune markers: IgM and IgG, the C3 complement fraction, circulating immune complexes, autoantibodies (antinuclear autoantibodies, anti-double stranded DNA autoantibodies, anti-smooth muscle autoantibodies, anti-neutrophilic cytoplasm autoantibodies, anti-cardiolipin autoantibodies, anti-parietal cell autoantibodies), and lymphocyte subtypes.

[Immunopathologic mechanism in some ocular diseases].

Objectives: The goal of the present study is to elucidate the pathogenic mechanisms that determine the ocular involvement in some systemic diseases.

Material And Methods: We have studied 45 patients with ocular diseases and concomitant systemic diseases (systemic lupus erythematosus-SLE, ankylosing spondylitis, Reiter syndrome, juvenile rheumatoid arthritis, Sjögren syndrome). The patients studied have been compared with a control group represented by 20 healthy individuals.