Differences and Similarities in Epidemiology and Risk Factors for Cutaneous and Uveal Melanoma.

Both cutaneous melanoma (CM) and uveal melanoma (UM) represent important causes of morbidity and mortality. In this review, we evaluate the available knowledge on the differences and similarities between cutaneous melanoma and uveal melanoma, focusing on the epidemiological aspects and risk factors. Uveal melanoma is a rare condition but is the most prevalent primary intra-ocular malignant tumor in adults.

COVID-19 immunization in people with cancer-Is it safe and efficient? What do we know?

Prior to the COVID-19 pandemic, vaccination of people with cancer or a recent history of cancer was advisable under specific conditions, depending on the type of vaccine (inactivated or live attenuated virus or bacterium), type of cancer, and whether they had undergone treatment for cancer. Some malignancies, especially hematological malignancies, and cancer treatments such as chemotherapy, radiotherapy, and splenectomy negatively impact the immune response. The clinical trials of currently used vaccines against COVID-19 did not include people with active cancer; thus, there is an important gap in the knowledge of safety and efficiency data for COVID-19 immunization in this population.

Magnetic Composite Scaffolds for Potential Applications in Radiochemotherapy of Malignant Bone Tumors.

: Cancer is the second leading cause of death globally, an alarming but expected increase. In comparison to other types of cancer, malignant bone tumors are unusual and their treatment is a real challenge. This paper's main purpose is the study of the potential application of composite scaffolds based on biopolymers and calcium phosphates with the inclusion of magnetic nanoparticles in combination therapy for malignant bone tumors.

THERMOPLASTIC MATERIALS APPLICATIONS IN RADIATION THERAPY.

This is an example of the use of thermoplastic materials in a high-tech medicine field, oncology radiation therapy, in order to produce the rigid masks for positioning and immobilization of the patient during simulation of the treatment procedure, the imaging verification of position and administration of the indicated radiation dose. Implementation of modern techniques of radiation therapy is possible only if provided with performant equipment (CT simulators, linear accelerators of high energy particles provided with multilamellar collimators and imaging verification systems) and accessories that increase the precision of the treatment (special supports for head-neck, thorax, pelvis, head-neck and thorax immobilization masks, compensating materials like bolus type material). The paper illustrates the main steps in modern radiation therapy service and argues the role of thermoplastics in reducing daily patient positioning errors during treatment.

EVOLUTION OF SYNCHRONOUS BILATERAL BREAST CARCINOMA IN A YOUNG PATIENT.

Bilateral breast cancer incidence is appreciated to be between 0.3 to 12% and is determined either by a hereditary load associated with chromosomal instability under the effect of environmental factors, or by the evolution in a particular hormonal context which gives biological aggressiveness. We present the case of a patient, aged 38 years, clinically, imagistic and bioptic diagnosed with left axillary lymph node metastases of breast carcinoma NST invasive G3, IHC-RE = 60%, RP = 30%, HER2neu = 2 +, Ki67 = 20%, in August 2013.

Pulmonary rehabilitation and quality of life in lung cancer patients.

Lung cancer is one of the most common types of cancer, often diagnosed in advanced stages. Chest surgery is the main component of curative treatment, the pre-operative functional status being predictive for post-operative morbidity. The potential benefits of pulmonary rehabilitation in lung cancer management appear in pre-operative period, improving the exercise capacity and increasing the number of patients sent to surgery, in post-operative period, decreasing the number of complications, and during the medical treatment of patients with advanced disease, improving the symptoms and increasing the quality of life.

[Multi-modal treatment in breast cancer. The prognostic role and correlation between relapse and metastasis].

Aim: The main aim of this study is to analyze the prognostic role of the treatment in breast cancer.

Material And Methods: Retrospective study of 445 patients with breast cancer with 3 categories of treatments.

Results: Statistic correlation between treatment categories and overall survival, high correlation between treatment and disease free survival.

[Superficial microwaves hyperthermia tumoral temperature distribution by using finite element analysis].

Unlabelled: The main aim of this study is to present a virtual method for tumor temperature distribution by using finite element analysis.

Material And Methods: First step is geometrical synthesis that means tumor and neighbor structures three-dimensional reconstruction using CT sections; the second represent temperature and material synthesis: temperature values application and tissues density, thermal conductivity, specific heat values application, then finite element analysis.

Results: Finite element analysis indicate tumor temperature distribution with maximum and minimum values as a result of microwave hyperthermia treatment.

[Superficial microwaves hyperthermia--physical treatment parameters obtained on experimental phantom].

Aim: To present the physical treatment parameters of superficial hyperthermia device that may be used in cancer treatment in association with radiotherapy.

Material And Methods: First step is to present the way to measure continuous temperature, the deep and surface temperature distribution obtained by using hyperthermia device. Second step is to describe the experimental protocol.

[Microwaves hyperthermia. Preliminary experimental results].

Aim: The main aim of this study was to present a way of designing a hyperthermia device based on microwaves, which will be used for cancer treatment in association with radiotherapy.

Material And Methods: A hyperthermia device with two parts - the electrical part and the mechanical support--was built. The surface temperature distribution was evaluated using a plastic material with micro-pockets filled with water.