Particularities of associating viral hepatitis with pregnancy and mental disorders.

Pregnancy generates particular circumstances for all co-existent conditions. Associating pregnancy with liver diseases has distinct particularities. The authors will perform a presentation of the etiopathogenic, diagnosis and therapeutic conduct particularities regarding the association between pregnancy, chronic liver diseases and mental disorders.

Circadian malfunctions in depression - neurobiological and psychosocial approaches.

Depression leads to disturbances in physiological rhythms, which result in disturbances in circadian sleep-wake cycles, hormonal secretion patterns and fluctuations in mood, all of which can be objectively measured. These disturbances, which are associated with depression, can be also used to define depression. Beyond these "transversal" time-related symptoms, there are the "longitudinal" time-related symptoms, since depression evolves over a long period of time, with a profound impact on a person's life and is often associated with long-term psychosocial consequences (Mendlewicz, 2010).

Current understanding of the neurobiology of major depressive disorder.

Depression is highly prevalent worldwide and associated with significant morbidity and mortality. Approximately 340 million people worldwide suffer from depression at any given time. Based on estimates from the World Health Organization (WHO), depression is responsible for the greatest proportion of burden associated with non-fatal health outcomes and accounts for approximately 12% total years lived with disability.