Publications by authors named "Anca D Stoica"
(Hp), a well-known human pathogen, causes one of the most common chronic bacterial infections and plays an important role in the emergence of chronic progressive gastric inflammation and a variety of gastrointestinal diseases. The prevalence of Hp infection varies worldwide and is indirectly proportional to socio-economic status, especially during childhood. The response to the eradication therapy significantly depends on the antibiotic resistance specific to each geographical region; thus, currently, given the increasing prevalence of antimicrobial resistance (especially to clarithromycin, metronidazole, and levofloxacin), successful treatment for Hp eradication has become a real challenge and a critical issue.
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- Hemoglobin-based oxygen carriers (HBOCs) are being explored for treating severe blood loss, with past research suggesting that hemerythrin (Hr) from marine worms could be a more effective alternative to traditional hemoglobin (Hb) in these applications.
- Recent experiments tested Hr polymers in hemorrhage situations, showing that while one Hr-based formulation worsened survival rates, an Hr-albumin copolymer restored survival rates to 100% and performed similarly to Hb-based products in most tests.
- The study indicates a potential solution to an acid-base issue linked to the Hr-albumin copolymer by suggesting the use of allogeneic albumin instead of human albumin, which could improve its efficacy as an oxygen