Health inequities in the diagnosis and outcome of sepsis in Argentina: a prospective cohort study.

Background: Socioeconomic variables impact health outcomes but have rarely been evaluated in critical illness. Low- and middle-income countries bear the highest burden of sepsis and also have significant health inequities. In Argentina, public hospitals serve the poorest segment of the population, while private institutions serve patients with health coverage.

Predictive Validity of Sepsis-3 Definitions and Sepsis Outcomes in Critically Ill Patients: A Cohort Study in 49 ICUs in Argentina.

Objectives: The new Sepsis-3 definitions have been scarcely assessed in low- and middle-income countries; besides, regional information of sepsis outcomes is sparse. Our objective was to evaluate Sepsis-3 definition performance in Argentina.

Design: Cohort study of 3-month duration beginning on July 1, 2016.

[Creutzfeldt-Jakob encephalopathy with mutation E200K. Report of a "sporadic" case].

Introduction: Creutzfeldt Jakob disease (CJD) has the highest incidence of the whole group of transmissible spongiform encephalopathies or prion diseases, which have the unique feature among all pathologies, to be able to appear as infectious/iatrogenic, sporadic or hereditary, being common to all, the deposition of an abnormal prion protein (PrPSc,CJres) in the central nervous system. More than 20 mutations of the gene (PRNP) that encodes the prion protein have been described. We here report a case of CJD(E200K) refered as probable 'sporadic' according to WHO.