Publications by authors named "Anat Maytal"

Purpose: To assess the risk for intraoperative and postoperative ocular bleeding associated with direct oral anticoagulant treatment in patients undergoing phacoemulsification surgery.

Methods: Consecutive patients had phacoemulsification and intraocular lens implantation while taking uninterrupted direct oral anticoagulants (dabigatran, rivaroxaban, or apixaban). Gender and age-matched patients without antithrombotic therapy were used as the control group.

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Article Synopsis
  • Keratoglobus is a rare eye condition causing corneal thinning and bulging, leading to vision loss and potential corneal perforation, but its genetic causes are not yet known.
  • The study analyzed 3 families with keratoglobus to identify its genetic basis, involving advanced sequencing techniques and mouse models.
  • Results revealed that mutations in the TMEM45A gene are associated with the disorder, with significant gene expression differences observed in affected corneas compared to healthy tissue.
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