Publications by authors named "Anastasios Soldatos"
Article Synopsis
- Vaccine pharmacovigilance involves monitoring adverse events related to vaccines, which can be complicated by community practices and public health policies; the study aimed to explore these challenges and the influence of socioeconomic factors.
- Researchers analyzed over 607,000 adverse event reports and found that 12.6% of events were serious, with polypharmacy (use of multiple medications) being a significant concern, affecting nearly 9% of cases.
- The study suggests improvements in integrating vaccine data and emphasizes the need for better digital services and socioeconomic considerations to enhance vaccine safety monitoring and public health communication.
Recently we demonstrated that lipopolysaccharide (LPS) promotes activation of the Ras/ERK cascade in medfly hemocytes and that phagocytosis of Escherichia coli by insect hemocytes is mediated by an integrin-dependent process via the activation of FAK/Src complex (J Biol Chem 273 (1998) 14813; FEBS Letters 496 (2001) 55). In the current study we wanted to further elucidate the effects of LPS on medfly hemocytes, in order to better understand the regulation of the evolutionary conserved signaling mechanisms between insects and mammals. We initially observed that different stimuli, including LPS, E.
View Article and Find Full Text PDFA doublet of medfly hemocyte proteins with a molecular mass of about 55 and 50 kDa were precipitated with LPS. Antibodies raised against human CD14 recognize the same doublet of proteins. These results support that mammalian CD14 and the doublet of protein bands in medfly hemocytes share common epitopes.
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