(Mello-Leitão) () spider web, a potentially attractive tissue engineering material, was investigated using quantitative peak force measurement atomic force microscopy and scanning electron microscopy with energy dispersive spectroscopy both in its natural state and after treatment with solvents of different protein affinities, namely, water, ethanol, and dimethyl sulfoxide (DMSO). Native silk threads are densely covered by globular objects, which constitute their inseparable parts. Depending on the solvent, treating modifies its appearance.
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