Publications by authors named "Anastasiia Kovaleva"
Osteoporosis is characterized by increased resorption and decreased bone formation; it is predominantly influenced by genetic factors. G-protein coupled receptors (GPCRs) play a vital role in bone homeostasis, and mutations in these genes are associated with osteoporosis. This study aimed to investigate the impact of single nucleotide polymorphism (SNP) rs1042713 in the gene, encoding the beta-2-adrenergic receptor, on osteoblastogenesis.
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- Human pluripotent stem cells (hPSCs) can differentiate into any adult tissue, making them important for regenerative medicine and research into factors affecting their growth and characteristics.
- The study analyzed the migration patterns of three hPSC cell lines (AD3, CaSR, and H9) through bright-field imaging, focusing on their "good" and "bad" morphological phenotypes.
- Results showed that migration speed varied based on the cell line and growth environment, with notable differences in migration behavior between "good" and "bad" colonies, particularly in specific culture conditions.
Angiogenesis is the development of new blood vessels from pre-existing ones. It is a complex multifaceted process that is essential for the adequate functioning of human organisms. The investigation of angiogenesis is conducted using various methods.
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