Publications by authors named "Anastasiia Dmytrivna Shkodina"
Compounds isolated from natural sources have been used for medicinal purposes for many centuries. Some metabolites of plants and microorganisms possess properties that would make them effective treatments against bacterial infection, inflammation, cancer, and an array of other medical conditions. In addition, natural compounds offer therapeutic approaches with lower toxicity compared to most synthetic analogues.
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- - Parkinson's disease (PD) is increasingly common in older adults, and recent research indicates that disruptions in circadian rhythms are prevalent among PD patients and may influence the disease's progression.
- - This review summarizes findings on clock gene expression in both PD patients and animal models, highlighting the potential impact of these genes on PD development and symptoms, along with discussions on epigenetic analyses and gene variants.
- - Furthermore, the review explores how clock genes affect mitochondrial function and hormone secretion, which could be linked to PD, while also noting the limitations of current studies and suggesting directions for future research.