Short-term progression of optic disc and macular changes in optic nerve head drusen.

Purpose: To quantify in patients with optic nerve head drusen (ONHD)changes after 1-year observation in: (i) optic disc and (ii) macular optical coherence tomography (OCT) parameters and (iii) the effect of age at enrolment in the study.

Design: Prospective, cross-sectional observational study using Spectral Domain-OCT (Copernicus; OPTOPOL Technology S.A.

Detection and characterisation of optic nerve and retinal changes in primary congenital glaucoma using hand-held optical coherence tomography.

Objective: To investigate (1) the feasibility of scanning the optic nerve (ON) and central retina with hand-held optical coherence tomography (HH-OCT) without sedation or anaesthesia in primary congenital glaucoma (PCG), (2) the characteristics of ON changes in comparison with adult primary open-angle glaucoma (POAG) in comparison with matched controls, (3) the sensitivity and specificity of ON parameters for diagnosis, and (4) changes of foveal morphology.

Methods And Analysis: HH-OCT (Envisu 2300; Leica Microsystems) was used to investigate ON and foveal morphology of 20 children with PCG (mean age 4.64±2.

Assessment of the anterior segment of patients with primary congenital glaucoma using handheld optical coherence tomography.

Purpose: To investigate the potential of handheld optical coherence tomography (HH-OCT) in assessing the anterior segment of the eye in patients with primary congenital glaucoma.

Design: A prospective, case-controlled observational study.

Participants: Twenty-two patients with primary congenital glaucoma (PCG, 9 females and 13 males; mean age 4.

Gender- and Ethnicity-Related Differences in Optic Nerve Head Topography in Healthy Indian and Caucasian Participants.

We investigated the effect of ethnicity and gender on optic nerve head morphology in healthy subjects using spectral-domain optical coherence tomography (SD-OCT). Thirty-five Indian (i.e.

Morphology of retinal vessels in patients with optic nerve head drusen and optic disc edema.

Purpose: We quantitatively investigated the peripapillary vascular morphology in patients with optic nerve head drusen (ONHD) and optic disc edema (ODE).

Methods: Computer-based fundus analysis was used to investigate peripapillary vascular morphology, including length, branching, and diameter of arteries and veins calibrated by optical coherence tomography.

Results: Patients with ONHD showed significantly larger diameters of arteries without branching (P = 0.

Normal macular structure measured with optical coherence tomography across ethnicity.

Objective: The difference in prevalence of various retinal pathologies in people of different ethnicity is well established. Optical coherence tomography (OCT) is a widely used technique that allows quantitative analysis of macular structure. In this study, we investigated macular layer morphology in healthy subjects using high-resolution spectral domain (SD) OCT across ethnicities comparing Asian (ie, Indian subcontinent) and Caucasian individuals.

Macular morphology in patients with optic nerve head drusen and optic disc edema.

Purpose: In this study we investigated macular morphology, including individual retinal layers, in patients with optic nerve head drusen (ONHD) and optic disc edema (ODE) compared with healthy participants, using high-resolution spectral domain optical coherence tomography (OCT).

Design: Prospective, cross-sectional, observational study.

Participants: A total of 67 patients with ONHD, 36 patients with ODE, and 57 healthy participants.