Publications by authors named "Anastasia M Khrustaleva"

The SNP variation in sockeye salmon across the Asian part of its range was studied in 23 samples from 16 lake-river systems of the West Pacific Coast to improve understanding of genetic adaptation in response to spawning watersheds conditions. Identification of candidate SNPs and environmental factors that can contribute to local adaptations in sockeye salmon populations was carried out using redundancy analysis (RDA), a powerful tool for landscape genetics proven to be effective in genotype-environment association studies. Climatic and hydrographic indices (7 indices in total), reflecting abiotic conditions in freshwater habitats of sockeye salmon and characterizing the temperature regime in the river basin, its variability during the year, the amount of precipitation, as well as the height of the maximum tide in the estuary, were used as predictor factors.

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BTB (bric-a-brack, Tramtrack, and broad complex) is a diverse group of protein-protein interaction domains found within metazoan proteins. Transcription factors contain a dimerizing BTB subtype with a characteristic N-terminal extension. The Tramtrack group (TTK) is a distinct type of BTB domain, which can multimerize.

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Article Synopsis
  • - Activation of local translation in neurites is crucial for long-term memory (LTM), with CPEB proteins like Orb2 playing a significant role in this process.
  • - Deletion of the 3'UTR of the Orb2 gene impairs LTM by reducing its protein levels in synapses, even though it remains unchanged in neuron soma.
  • - High-throughput sequencing revealed over 6000 potential mRNA targets of Orb2, suggesting that the 3'UTR is essential for the correct localization of Orb2 and other proteins necessary for LTM in neurons.
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